Andreas Czich - uventia

Andreas Czich

Andreas Czich

Andreas Czich

Toxicologist, Senior Distinguished Scientist


Andreas Czich is a Biochemist by training (PhD) with over 30 years Genetic Toxicology experience working over 20 years in pharmaceutical industry. At Sanofi he filled several roles in the preclinical Safety department, including heading the In silico, Investigative and Genetic Toxicology Team in Frankfurt/Germany. Currently he is the Scientific Advisor for Genetic Toxicology at Sanofi. In this role he is part of internal and external scientific/regulatory expert groups dealing with Hazard Identification and Risk Assessments of Nitrosamines and Mutagenic impurities in pharmaceuticals. In addition he is consulting internal project teams on strategies to assess the risk of all mutagenic impurities including Nitrosamines.

3rd Annual Genotoxic Impurities Nitrosamines & Beyond
November 30, 2023
Learn the best techniques and cutting-edge methods for reducing genotoxic and elemental impurities. Recording of 2 days event sessions [17 video sessions].

DAY 1: NOVEMBER 30th, 2023

SESSION: Toxicological assessment of nitrosamines

◆  Mutagenicity and Carcinogenicity of Nitrosamines.

◆  Mechanisms.

◆  Differences between small molecular weight Nitrosamines and NDSRI.

◆  The LTL concept.

◆  Using SAR, QM and Metabolism data to support AI.

◆  Improving the adherence to ICH M7.

Speaker Details
Speaker Details