Crystal DSilva

Crystal DSilva

Crystal D’Silva

Associate Director – Preclinical Toxicology

Baxter-Healthcare

Crystal D’Silva is a Preclinical subject matter expert at Baxter International and based in Brussels, Belgium. She is actively involved in standard development as a national expert in the ISO/TC 194 Biological and Clinical Evaluation of Medical Devices technical committee and she is part of several working groups within Medicines for Europe, MedTech Europe, and the International Generic and Biosimilars Association. She is also a European Registered Toxicologist (ERT) and a Diplomate of the American Board of Toxicology (DABT). She has a PhD in Medical Biophysics from the University of Toronto in collaboration with the Princess Margaret Cancer Centre and the Hospital for Sick Children (Ontario, Canada).

Speaked About
Genotoxic Impurities Nitrosamines
December 4, 2025
Two-day virtual event focused on the latest developments, technical challenges in genotoxic impurity control. Recording of 2 days event sessions [14 video sessions].
Expired

DAY 1: December 4th, 2025

SESSION: Toxicological Risk Assessment of N-Nitrosamines: Challenges and Perspectives

  Overview of toxicological risk assessment of nitrosamines.

  Comparison between agency- and literature-published acceptable intake values.

  Challenges with the current state of affairs and future perspectives.

  Weight-of-evidence approach in setting acceptable intake limits – NDBzA as a case study.

Genotoxic-Impurities-Nitrosamines-Beyond
December 4, 2024
Meeting with subject matter experts to evaluate different points of view on how to solve the problems associated with mutagenic impurities. Recording of 2 days event sessions [13 video sessions].
Expired

DAY 1: December 4th, 2024

SESSION: Toxicological Risk Assessment of Nitrosamines – Challenges and Perspectives

  Overview of toxicological risk assessment of nitrosamines.

  Comparison between agency- and literature-published acceptable intake values.

  Challenges with the current state of affairs and future perspectives.

Speaker Details
Speaker Details