Katherine Lovejoy is an Application Chemist at the Thermo Fisher Scientific production site for HPLC and for the charged aerosol detector. She has 7 years of experience in that role and enjoys helping others get the best possible CAD results. She earned a PhD in Inorganic Chemistry from the Massachusetts Institute of Technology and has a h-index of 15. Her experience also includes time as a chemist reviewer at the FDA and a scientist at Los Alamos National Laboratory.
DAY 1: MARCH 7th, 2024
SESSION: Implementation of a non-volatility test before quantitating E&L unknowns with a charged aerosol detector
◆ HPLC with 3 orthogonal detectors allows quantitation of unknowns by charged aerosol detectorand identification by easy-to-use low resolution MS
◆ Classification of unknowns as non-volatile or semi-volatile in the CAD reduces the uncertainty factor and improves quantification by surrogate standard.
◆ When using an inverse gradient, improved mixing with an inline capillary mixer after the merge point of the analytical and inverse gradients reduces inter-compound %RSD