Ian Ashworth

Ian Ashworth

Ian Ashworth

Principal Scientist

AstraZeneca

Career summary: Over thirty years of experience of applying physical organic chemistry to solve problems within a process chemistry environment, initially in speciality chemicals and agrochemicals, before moving to pharmaceuticals. Throughout an interest in pH dependent reactions and hydrolytic stability has been a recurring theme. Most recently this has been applied to the building mechanism-based models of nitrosamine formation in aqueous solution as tools to support drug substance and drug product risk assessments.
Academic Background: BSc in Chemistry from Durham University followed by a D Phil in Chemistry at Cambridge University with Tony Kirby, which provided an introduction to pH dependent kinetics.

Speaked About
December 2, 2026
Explore 2026 EMA trends, AI risk mapping, ppb-level LC-MS/MS, and advanced mitigation for nitrosamines and genotoxic impurity compliance.
Upcoming

DAY 2: December 3rd, 2026

SESSION: N-Nitrosamine Formation & Degradation in Pharmaceutical Drug Products: The Application of Models Based on Aqueous Kinetics

◆  General kinetic models of aqueous nitrous acid-based nitrosamine formation.

◆  Modelling nitrosamine formation in a solid drug productb.

◆  Stability of nitrosamines.

Speaker Details
Speaker Details